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Forty-nine manuscripts on a wide variety of subjects, heavily illustrated and with a subject index. Highlights include:
* Manuscript document signed by Bernal Diaz del Castillo, 1556.
* Unpublished archive of 56 manuscript Spanish royal decrees signed by Philip III and Philip IV to the Audiencia of Guatemala, 1600-1628.
* Substantial unpublished Spanish fencing manuscript, 1640
* Collection of 157 autograph letters signed by Innocéncio Francisco da Silva to one of his closest collaborators, 1856-1865.
* Massive unpublished manuscript history of medicine, ca. 1778.
* Significant literary archive of Júlio Dantas, 1880s-1950s.
Other specialties